For the third time in a row, a prostitute is found dead along the disco club strip in Quezon Avenue. Police detective Waldo (Mikey Arroyo) assigned to the case surmises that the murder is a serial killing which goes against the information gathered from the informant Budol (Patrick Ervie Mateo) by newspaper reporter Karen (Judy Ann Santos). Their differing views fueled the antagonism and professional rivalry between Karen and Waldo until they stumble upon the drug syndicate led by Bingo (Joko Diaz). Karen and Waldo escape into the woods as Bingo chases after them and in the midst of approaching danger, the former rivals begin to feel something special for each other.